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 TECHNOLOGIES
CHEMICALS
AND POLYMERS
CHROMATOGRAPHIC
SEPARATION TECHNOLOGY
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The unique characteristics and
distinctiveness of enantiomers is most commonly referred to as "chirality".
Chirality plays an increasingly important role in organic chemistry and
biology due to the fact that biological systems tend to be sterioselective
for only one enantiomer in a given pair.
This opportunity provides a patent-protected column material for
separating amino acids and other enantiomers using standard liquid
chromatographic techniques.
Patented Technology
Claim 1 of U.S. Patent
4,842,935
covers a wide range of crown ethers with the following formula,
where R is a hydrogen or alkyl group:
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Go to printable
pdf version of this
technology |
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Ar is an optically active divalent aromatic group:
Where A and B are each a hydrogen atom, an
alkyl group, or an aryl group. |
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Intellectual
Capital
On April 1, 2001, the National Institute of Advanced Industrial Science and
Technology began operations as the "new" AIST. The new AIST is a research
organization that comprises 15 research institutes previously under the
former Agency of Industrial Science and Technology in the Ministry of
International Trade and Industry and the Weights and Measures Training
Institute.
AIST is Japan's largest public research organization with research
facilities and more than 3,200 employees across Japan.
Benefits of
the Technology
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Optically-active lipophilic crown compounds adsorbed on standard liquid
chromatographic columns.
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Enables use of pure water or volatile dilute acids,
rather than organic solvents, as eluents.
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Aqueous amino acid solutions may be used for
separation.
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Low-cost preparation and production of the columns is
enabled using these compositions.
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Easy-to-prepare columns of silica, alumina, magnesia,
or silica-alumina.
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For More Information
AIST is seeking to license these technologies and assist
with their commercialization. A number of investment options are currently
under consideration.
Consideration will be provided to a range of financial, strategic, and
commercial investment partnerships. Certain circumstances will
warrant consideration for nominal funding from AIST.
Contact
Michael F Allan
First Principals, Inc.
1768 East 25th Street
Cleveland, Ohio 44114
216-881-8526 - Phone
216-881-8522 - Fax
Email: info@fmailto:info@firstprincipals.comirstprincipals.com
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